a well-known and popular steroid too. Like nandrolone it is most commonly used as a base compound to stack with other steroids. Methenolone, however, is a DHT-based steroid (actually DHB or dihydroboldenone, which reduces 5-alpha of the milder boldenone). Meaning when it interacts with the aromatase enzyme it does not belong to estrogens at all. This makes it ideal for use in cutting when excess estrogen is best because of the remanent effects on water and fat avoidance. Methenolone is mostly only used in such cases, or by people who are very succeptible to estrogenic side effects, because the anabolic effect of methenolone is slightly lower than that of nandrolone, most likely because it is not estrogenic. Since it is a widely available steroid its often used as a substitute for nandrolone or boldenone for those who do not have access to Deca-Durabolin or Laurabolin or Equipoise. When stacked with a heavy mass steroid such as testosterone and/or methandrostenolone it can deliver almost similar gains. Those who cut will most likely be very happy stacking with drostanolone, stanozolol or trenbolone.
Women and beginners also stack methenolone WITH nandrolone because this gives a mild anabolic stack, is generally considered one of the safer stacks to take in an androgenic perspective. But heck, with the nandrolone, also a very suppressive stack. Methenolone is available as an injection or as an oral. The injection is of course considered better. It is an enanthate ester that is quite long acting and only needs to be injected once a week in doses of 300-600 mg. Because it passes through the liver breakdown after the first pass, it also has a higher survival rate. The orals are much less convenient, but often preferred by bodybuilders who are afraid of needles or who are already taking one or more injectable compounds. The tabs are in a short-lived acetate form, which means that doses of 100-150 mg per day are needed, split into 2 or 3 doses, making the riders very uncomfortable for use. The reason doses need to be split, unlike most oral steroids, is because Methenolone is not 17-alpha-alkylated but 1-methylated for oral bioavailability. This reduces liver stress, but also availability, thus the varied and high doses needed daily.
Like nandrolone, methenolone is very mild on the system. Probably the reason why both strong and base compounds are favoured in batches. Methenolone has no estrogenic side effects whatsoever, due to its structure. The effects on cholesterol levels are barely noticeable. In doses of 200 mg or less (injectable) blood pressure is rarely, if ever, altered. As for hepatotoxicity, long-term use will naturally increase liver values but gradually and only slightly. The injections of course, since they only pass the liver once have about half the liver-toxic effects of the riders. The low liver toxicity is due to the bioavailability of methenolone being carried by a 1-methyl group, which reduces the need for a carrier facility such as a 17-alpha-acylated group, the main culprit in steroid-related liver ailments. The strangest thing to consider though, that Primo is still a DHT (or rather DHB) derivative, is that it is quite simply on the system androgenically too. Women use methenolone often, usually the tabs, and find little virilisation symptoms in short term use of methenolone. Long-term use may cause some acne and a deepening of the voice, however.
Methenolone is also not overly suppressive of the HPT axis (endocrine axis for the production of natural testosterone). These are both the result of DHB’s 1,2-double bond, which, analogous to the parent structure boldenone, reduces the androgenic binding by 50% compared to DHT. For athletes who wish to maintain a “natural” state in competition, the tablets will be quite as recognition chances for the acetate form are well suited quite slim. Tests have improved, however, and a whole range of metabolites1 of methenolone can be detected with a simple urine sample. But an English study documented that there is a liability in eating methenolone contaminated meats2 which could form a possible defence if found out. One could always claim they ate the meat of a chicken or cow injected with methenolone, since the test completed eating like meat does not improve performance, but can test positive for multiple methenolone metabolites almost 24 hours after ingestion. This is for those of you, a viable defence against a possible methenolone positive. Stacking and use: Methenolone comes in oral tests and injections.